8 net carbs

Chicken and broccoli alfredo casserole

Our low-carb chicken and broccoli alfredo casserole, features tender chicken, mushrooms, broccoli, and a creamy alfredo ranch sauce.

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Chicken and broccoli alfredo casserole

Low-carb chicken and broccoli alfredo casserole on a white dinner plate.

Low-carb chicken and broccoli alfredo casserole [Keto]

Total Diabetes Wellness
Our low-carb chicken and broccoli alfredo casserole offers a satisfying and flavorful option for those seeking a lighter meal without sacrificing taste. Combining tender chicken, mushrooms, broccoli, and a creamy alfredo ranch sauce, this dish is perfect for family dinners or meal prepping.
Prep Time 45 minutes
Cook Time 25 minutes
Total Time 1 hour 10 minutes
Course Lunch and Dinner
Cuisine American
Servings 8 servings
Net Carbs 8 g
*Net carbs are per serving


Alfredo sauce

  • ½ cup butter
  • 3 ounces cream cheese
  • 3 cups heavy cream
  • 1 teaspoon garlic powder
  • 2 teaspoons ranch seasoning mix
  • ½ cup parmesan cheese, grated


  • 6 cups shredded chicken (about 2 pounds of chicken)
  • 2 tablespoons olive oil
  • 1 small onion, diced
  • 16 ounces baby bella mushrooms, sliced
  • 1 ½ pounds broccoli florets, chopped into bite-size pieces
  • ½ cup parmesan cheese, grated


  • In a saucepan over low heat, melt the butter. Add the cream cheese and stir until melted. Stir in the heavy cream, whisking continuously until well combined. Add the garlic powder and ranch seasoning. Increase the heat and bring to a low boil. Decrease the heat and simmer, stirring often. Add in the parmesan cheese, and stir until melted. Remove from heat.
    Top view of mixing homemade alfredo sauce in a saucepan.
  • [If your chicken is not already cooked and shredded] - In a skillet over medium heat, spray with olive oil. Put in the chicken breast, sear each side for 2-3 minutes. Pour in 1/3 cup of water or chicken broth, reduce heat to medium-low, and cover the skillet with a lid. Check the chicken after 10 minutes with an instant-read thermometer, cook until the chicken reaches 165F/74C. Take it off the heat and let it rest for 5 minutes before shredding.
    Top view of shredded cooked chicken in a mixer bowl.
  • Preheat your oven to 400F/205C.
    Close-up view of temperature knob on an oven, preheat oven to cook a meal.
  • In a large skillet over medium heat, heat the olive oil. Add the onions and mushrooms, stirring for 3-5 minutes. Add the broccoli florets and stir to combine. Cook for another 3-5 minutes or until the broccoli is crisp-tender and bright green.
    Top view of a skillet with onions, mushrooms, and broccoli sautéing.
  • Spread the shredded chicken in a large casserole dish to cover the bottom. Layer the sautéed mushrooms, onions, and broccoli mixture on top of the chicken.
    Top view of large casserole dish with chicken and vegetables layered on top.
  • Pour the alfredo sauce over the vegetable mixture in the casserole dish, then sprinkle Parmesan cheese on top.
    Top view of low-carb chicken and broccoli alfredo casserole in a casserole dish ready to bake.
  • Bake the casserole for 20-25 minutes until the sauce is bubbling. Enjoy!
    Top view of low-carb chicken and broccoli alfredo casserole just out of the oven, ready to eat.



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Keywords Broccoli, Chicken, and Mushroom Casserole, Chicken and Broccoli casserole, Keto chicken alfredo, Low-carb chicken alfredo
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Photos of Low-Carb Chicken and Broccoli Alfredo Casserole


Heavy cream

Pay attention to the carbohydrate count in the brand of heavy cream you select. Some brands have sugar added, which can drastically affect the carb count and will change the nutritional value of this recipe.

Frequently Asked Questions

Is this chicken and broccoli alfredo casserole recipe Keto?

Yes, we consider this recipe Keto. One serving of this chicken and broccoli alfredo casserole has 8 grams of net carbs, which is appropriate for a main dish on a Keto diet.

Is this recipe gluten-free?

Yes! This recipe is naturally gluten-free.

Storage and Reheating Guidelines

  • Make-ahead: Prepare the casserole ahead of time and store it in the refrigerator, covered, for up to 2 days before baking.
  • Storing leftovers: Store any remaining casserole in an airtight container in the refrigerator for up to 3-4 days.
  • Freezing instructions: The casserole can be frozen for longer storage. Transfer it to a freezer-safe container or tightly wrap it in plastic wrap and aluminum foil. Freeze for up to 2-3 months.
  • To reheat: Thaw the frozen casserole overnight in the refrigerator before reheating. Reheat individual servings in the microwave or warm the entire casserole in the oven at 350F/175C until heated through.

Additional Details

The low-carb chicken and broccoli alfredo casserole is a hearty yet nutritious dish that combines tender chicken, vibrant broccoli, earthy mushrooms, and a creamy alfredo ranch sauce. Packed with protein, fiber, and healthy fats, this casserole is a wholesome meal option that can easily fit into a low-carb eating plan.


The low-carb chicken and broccoli alfredo casserole is crafted from a selection of wholesome ingredients, each offering unique benefits:

  • Chicken: Packed with high-quality protein, chicken serves as the mainstay of this dish, promoting muscle health and providing essential amino acids for overall well-being.
  • Broccoli: Bursting with vitamins C and K, as well as fiber, broccoli adds a vibrant pop of color and a nutritious boost to the casserole, supporting immune function and digestive health.
  • Mushrooms: Baby bella mushrooms not only lend a rich, earthy flavor to the dish but also boast an array of health benefits, including immune-boosting properties and potential anti-inflammatory effects.
  • Parmesan cheese: A sprinkle of grated parmesan cheese adds a savory depth to the casserole while also contributing a dose of calcium and protein for bone health and muscle function.

Benefits for people with diabetes

Our low-carb chicken and broccoli alfredo casserole offers several benefits for individuals managing diabetes:

  • Low-carb profile: With its emphasis on protein and vegetables, this casserole is naturally low in carbohydrates, making it easier to manage blood sugar levels.
  • High in protein: Protein helps slow down the absorption of carbohydrates, which can help prevent spikes in blood sugar levels after meals.
  • Nutrient-dense ingredients: The dish is loaded with nutrient-dense ingredients like chicken, broccoli, and mushrooms, providing essential vitamins, minerals, and antioxidants that support overall health.
  • Balanced macronutrients: By incorporating a balance of protein, fats, and fiber-rich vegetables, this casserole promotes satiety and helps regulate blood sugar levels throughout the day.


While the classic recipe is a crowd-pleaser on its own, there are endless possibilities for customization to suit individual preferences and dietary needs. Consider the following variations:

  • Vegetarian option: Omit the chicken and add extra vegetables like bell peppers, zucchini, or spinach for a vegetarian-friendly version.
  • Spice it up: Add a kick of heat by incorporating diced jalapeños or red pepper flakes into the alfredo sauce for a spicy twist.
  • Dairy-free option: To make this casserole dairy-free, substitute the butter, cream cheese, and parmesan cheese in the alfredo sauce with dairy-free alternatives such as vegan butter, cashew cream, or nutritional yeast. You can also omit the cheese topping altogether or use a dairy-free cheese alternative for those who are lactose intolerant or have dairy allergies.
  • Turkey and bacon twist: For a flavorful twist on the classic recipe, substitute the chicken with ground turkey and add crispy bacon pieces to the casserole layers. The addition of bacon lends a smoky, savory flavor that complements the creamy alfredo sauce perfectly.
  • Shrimp and sausage medley: Elevate the dish with a seafood and sausage medley by incorporating shrimp and Italian sausage into the casserole layers. Sauté the shrimp and sliced Italian sausage in a skillet with olive oil, garlic, and Italian seasoning until cooked through and lightly browned, then layer them with the broccoli and mushroom mixture in the casserole dish. The combination of juicy shrimp and flavorful sausage adds a dynamic twist to the dish, offering a delicious alternative for seafood and meat lovers alike.

Serving suggestions

Enhance your dining experience with these serving suggestions:

  • Pair with a side salad: Serve the casserole with a crisp green salad dressed with a light vinaigrette for a refreshing contrast.
  • Serve with cauliflower rice: Accompany the casserole with cauliflower rice for a low-carb alternative to traditional rice.
  • Garnish with fresh herbs: Sprinkle chopped fresh parsley or basil on top of the casserole before serving for a pop of color and flavor.

Our low-carb chicken and broccoli alfredo casserole is not only a delicious and satisfying meal option but also a diabetic-friendly choice that aligns with a low-carb lifestyle. With its nutrient-dense ingredients, balanced macronutrients, and versatility, this casserole is sure to become a staple in your diabetes-friendly meal rotation.

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